- A vaccine that sits on the shelf is useless.
— Albert Sabin
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Mission
The Aeras Global TB Vaccine Foundation is a non-profit Product Development Partnership (PDP) dedicated to the development of effective TB vaccine regimens that will prevent tuberculosis in all age groups and will be affordable, available and adopted worldwide.
Goal
The goal of the Aeras Global TB Vaccine Foundation is to develop, test, characterize, license, manufacture and distribute at least one new TB vaccine regimen for infants and another for adolescents by 2016 and ensure their availability to all who need them.
Objectives
- To advance the world's leading TB vaccine candidates forward towards licensure and availability by reviewing data from clinical trials and selecting only the most promising candidates for large-scale Phase III trials.
- To rationalize the TB vaccine development process by attempting to validate animal models and immunologic markers capable of predicting vaccine induced protection in humans which will make possible rapid and rational development of more effective vaccines in the future.
- To maintain a robust TB vaccine pipeline so that subsequent generations of vaccines that have better performance and/or potential to prevent reactivation of latent infection will be brought forward.
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